ENGINEERING OF HELICOBACTER PYLORI L-ASPARAGINASE: CHARACTERIZATION OF TWO FUNCTIONALLY DISTINCT GROUPS OF MUTANTS.

Engineering of Helicobacter pylori L-asparaginase: characterization of two functionally distinct groups of mutants.

Bacterial L-asparaginases have been used as anti-cancer drugs for over 4 decades though presenting, along with their therapeutic efficacy, several side effects due to their bacterial origin and, seemingly, to their secondary glutaminase activity.Helicobacter pylori type II L-asparaginase possesses interesting features, among which a reduced catalyt

read more

Fish oil enhances recovery of intestinal microbiota and epithelial integrity in chronic rejection of intestinal transplant.

BACKGROUND: The intestinal chronic rejection (CR) is Tracksuit the major limitation to long-term survival of transplanted organs.This study aimed to investigate the interaction between intestinal microbiota and epithelial integrity in chronic rejection of intestinal transplantation, and to find out whether fish oil enhances recovery of intestinal m

read more


Association between Loneliness and Memory Function through White Matter Hyperintensities in Older Adults: The Moderating Role of Gender

Loneliness has an important impact on memory function in late life.However, the neural mechanism by which loneliness detrimentally influences memory function remains elusive.Furthermore, it remains unclear whether the association between loneliness and memory function varies by gender.The Building Set current study aimed to investigate the neural m

read more